Pesquisadores desenvolvem uma insulina oral para o tratamento de diabetes

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Pesquisadores da Universidade de Sydney, na Austrália, estão desenvolvendo uma insulina oral,

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que pode ser uma revolução no tratamento de pacientes com diabetes que precisam fazer o uso do medicamento na forma injetável para controlar o nível de glicose no sangue

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Segundo os especialistas ouvidos pela Agência Einstein, os efeitos obtidos com o animais dão indícios de que a nova forma de utilização da insulina leva vantagem sobre a injetável

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porque entrega o hormônio diretamente no fígado, onde pode ser absorvido ou entrar na circulação sanguínea

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O diabetes é uma doença crônica caracterizada pela produção ineficiente ou pela resistência à ação da insulina,

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o hormônio produzido pelo pâncreas, que controla a quantidade de glicose no sangue para fornecer energia ao corpo humano

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Segundo dados da pesquisa Vigitel Brasil 2023 (Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico), 10,2% da população brasileira tem diabetes

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Até agora o uso da insulina por via oral não era uma possibilidade, pois a substância é uma proteína, o que faz com que ela sofra a digestão no estômago e não consiga chegar intacta ao fígado, onde deve agir

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“Por isso, os pesquisadores desenvolveram nanopartículas que conseguem resistir a esse processo e são absorvidas adequadamente”, explica o endocrinologista Simão Lottenberg, do Hospital Israelita Albert Einstein

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